Amisulpride is a member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist.
General Information: –
CAS No – 71675-85-9
Molecular Formula / Molecular Weight – C17H27N3O4S = 369.48
Physical State (20 deg.C) – Solid
Storage Temperature – 0-10°C
Condition to Avoid – Heat Sensitive
PubChem Substance ID – 135727298
Specifications: –
Appearance – White to Almost white powder to crystal
Purity(HPLC) – min. 98.0 area%
Purity(Nonaqueous Titration) – min. 98.0 %
Melting point – 125.0 to 129.0 °C
Applications: –
Amisulpride, a substituted benzamide derivative, is a selective dopamine D2/D3 receptors antagonist. Amisulpride binds selectively to dopaminergic D2 and D3 receptor subtypes without any affinity for D1, D4 and D5 receptor subtypes, in limbic system. Amisulpride is devoid of affinity for serotonin receptors or other neurogenic receptors such as histamine, cholinergic and adrenergic receptors. Recently, the amisulpride antagonism of 5-HT7 receptors has been reported. (The product is for research purpose only.)